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Showing posts with label disease. Show all posts
Showing posts with label disease. Show all posts

Monday, August 4, 2014

Type 2 Diabetes Facts and Figures

















What is diabetes?

Diabetes is a group of diseases marked by high levels of blood glucose resulting from defects in
insulin production, insulin action, or both. Diabetes can lead to serious complications and
premature death, but people with diabetes can take steps to control the disease and lower the risk
of complications.

SOURCE: National Diabetes Education Program, Snapshot of Diabetes, Retrieved on February 18, 2014, from, http://ndep.nih.gov/media/fs_gensnapshot.pdf

Type 2 diabetes is the most common form of the disease. In type 2 diabetes, either your body
does not produce enough insulin or the cells ignore the insulin. This is called insulin resistance.
Insulin is necessary for the body to be able to use glucose for energy. When you eat food, the
body breaks down all of the sugars and starches into glucose, which is the basic fuel for the cells
in the body. Insulin takes the sugar from the blood into the cells. When glucose builds up in the blood instead of going into cell, it can cause two problems:

• Right away, your cells may be starved for energy.
• Over time, high blood glucose levels may hurt your eyes, kidneys, nerves or heart.
Some groups have a higher risk for developing type 2 diabetes than others. Type 2 diabetes is
more common in African Americans, Latinos, Native Americans, and Asian Americans/Pacific
Islanders, as well as the aged population.

SOURCE: American Diabetes Association, Diabetes Basics – Facts About Type 2, Retrieved on February 18, 2014, from, http://www.diabetes.org/diabetes-basics/type-2/

Current Facts & Figures

• 25.8 million Americans have diabetes – 8.3% of the U.S. population. Of these, 7 million
do not know they have the disease.
• 215,000 Americans younger than 20 have been diagnosed with diabetes. Most cases of
diabetes among children and adolescents are type 1.
• The number of people diagnosed with diabetes has risen from 1.5 million in 1958 to 18.8
million in 2010, an increase of epidemic proportions.
• It is estimated that 79 million adults aged 20 and older have pre-diabetes. Pre-diabetes is
a condition where blood glucose levels are higher than normal but not high enough to be
called diabetes. Studies have shown that by losing weight and increasing physical activity
people can prevent or delay pre-diabetes from progressing to diabetes.
• Type 1 (previously called insulin-dependent or juvenile-onset) diabetes accounts for
approximately 5% of all diagnosed cases of diabetes in adults.
Type 2 (previously called non-insulin-dependent or adult-onset) diabetes accounts for
90% to 95% of all diagnosed cases of diabetes in adults. Type 2 diabetes is increasingly
being diagnosed in children and adolescents.
• Gestational diabetes occurs in 2% to 10% of pregnancies. Women who have had
gestational diabetes have a 35% to 60% chance of developing diabetes, most type 2, in
the next 10-20 years.
• Diabetes is the seventh leading cause of death listed on U.S. death certificates.
• Cardiovascular disease is the leading cause of death among people with diabetes – about
68% die of heart disease or stroke.
• Total health care and related costs for the treatment of diabetes run about $174 billion
annually.
SOURCE: National Diabetes Education Program, Snapshot of Diabetes, Retrieved on February 18, 2014, from, http://ndep.nih.gov/media/fs_gensnapshot.pdf

Warning Signs & Symptoms

Early detection and treatment of diabetes can decrease the risk of developing the complications
of diabetes. The following symptoms of diabetes are typical. However, some people with type 2
diabetes have symptoms so mild that they go unnoticed.
Common symptoms of diabetes:
• Urinating often
• Feeling very thirsty
• Feeling very hungry – even though you are eating
• Extreme fatigue
• Blurry vision
• Cuts/bruises that are slow to heal
• Weight loss – even though you are eating more (type 1)
• Tingling, pain, or numbness in the hands/feet (type 2)
SOURCE: American Diabetes Association, Diabetes Basics – Symptoms, Retrieved on February 18, 2014, from, http://www.diabetes.org/diabetes-basics/symptoms/

Complications

Heart disease and stroke

• Adults with diabetes have heart disease death rates about 2 to 4 times higher than adults
without diabetes.
• The risk for stroke is 2 to 4 times higher among people with diabetes.
High blood pressure
• In 2005-2008, of adults aged 20 years or older with self-reported diabetes, 67% had blood
pressure greater than or equal to 140/90 mmHg or used prescription medications for
hypertension.

Blindness

• Diabetes is the leading cause of new cases of blindness among adults aged 20-74 years.
• In 2005-2008, 4.2 million (28.5%) people with diabetes aged 40 years or older had
diabetic retinopathy, and of these, almost 0.7 million (4.4% of those with diabetes) had
advanced diabetic retinopathy that could lead to severe vision loss.

Kidney disease

• Diabetes is the leading cause of kidney failure, accounting for 44% of new cases in 2008.
• In 2008, 48, 374 people with diabetes began treatment for end-stage kidney disease in the
United States.
• In 2008, a total of 202, 290 people with end-stage kidney disease due to diabetes were
living on chronic dialysis or with a kidney transplant in the United States.
Nervous system disease (Neuropathy)

• About 60% to 70% of people with diabetes have mild to severe forms of nervous system
damage.
Amputation

• More than 60% of nontraumatic lower-limb amputations occur in people with diabetes.
• In 2006, about 65,700 nontraumatic lower-limb amputations were performed in people
with diabetes.

SOURCE: American Diabetes Association, Diabetes Basics –Statistic, Retrieved on February 18, 2014, from, http://www.diabetes.org/diabetes-basics/statistics/

Diabetes Prevention

Research studies have found that moderate weight loss and exercise can prevent or delay type 2
diabetes among adults at high-risk of diabetes. The Diabetes Prevent Program (DPP), a major
federally funded study of 3,234 people at high risk for diabetes, showed that people can delay
and possibly prevent the disease by losing a small amount of weight (5% to 7% of total body
weight) through 30 minutes of physical activity 5 days a week and healthier eating.

Anyone aged 45 years or older should consider getting tested for diabetes, especially if you are
overweight. If you are younger than 45, but are overweight and have one or more of the
additional risk factors (see below), you should consider getting tested.

What are the risk factors which increase the likelihood of developing diabetes?
• Being overweight or obese.
• Having a parent, brother, or sister with diabetes.
• Being African American, American Indian, Asian American, Pacific Islander, or
Hispanic American/Latino heritage.
Having a prior history of gestational diabetes or birth of at least one baby weighing more
than 9 pounds.
• Having high blood pressure measuring 140/90 or higher.
• Having abnormal cholesterol where HDL (“good”) cholesterol is 35 or lower, or
triglyceride level is 250 or higher.
• Being physically inactive – exercising fewer than three times a week.

SOURCE: Centers for Disease Control and Prevention, Diabetes Home – Diabetes & Me, Prevent Diabetes. Retrieved on February 18, 2014, from, http://www.cdc.gov/diabetes/consumer/prevent.htm

For More Information

• American Diabetes Association
http://www.diabetes.org/

• National Diabetes Educational Program
http://ndep.nih.gov/

• Centers for Disease Control and Prevention
http://www.cdc.gov/

• National Diabetes Information Clearinghouse
http://www.diabetes.niddk.nih.gov/

• Juvenile Diabetes Research Foundation
http://jdrf.org/




Eric Dempsey
Master Sergeant, U.S. Army Retired
NASM Certified Personal Trainer and Weight Loss Specialist
Graduate Student In Exercise Science At Cal U.
Dempseys Resolution Fitness
www.dempseysresolution.com


Monday, December 12, 2011

Inflammation: The Silent Killer and Obesity


Inflammation is part of the complex biological response of vascular tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. Inflammation is a protective attempt by the organism to remove the injurious stimuli and to initiate the healing process.

Acute inflammation is characterized by the redness, heat, swelling, and pain that is the immune system’s normal response to infection or injury. Immune cells congregate at the site so that they can overwhelm and dispose of infectious organisms or debris from injury. Thus healing takes place. But there is another kind of inflammation which is chronic and "systemic." It’s been the topic of many studies and discussion lately. This is the kind that you can't see but it is there lurking and destroying from within.

Although it is not proven that inflammation causes cardiovascular disease, inflammation is common for heart disease and stroke patients and is thought to be a sign or atherogenic response. It’s important to know what inflammation is and what it can do to your heart.
One inflammation-blood pressure study indicates that a person’s current level of C-reactive protein (CRP) – a key player in inflammation – can indicate future high blood pressure development. In fact, the study’s researchers suggest high blood pressure may be an inflammatory disorder.
The worldwide prevalence of obesity and related metabolic disorders is rising rapidly, increasing the burden on our healthcare system. Obesity is often accompanied by excess fat storage in tissues other than adipose tissue, including liver and skeletal muscle, which may lead to local insulin resistance and may stimulate inflammation. In addition, obesity changes the composition of adipose tissue, leading to changes in protein production and secretion. Some of these secreted proteins, including several proinflammatory mediators, may be produced by macrophages resident in the adipose tissue. The changes in inflammatory status of adipose tissue and liver with obesity feed a growing recognition that obesity represents a state of chronic low-level inflammation.

Obesity is closely linked to fat storage in liver and is nowadays considered as a major risk factor for the development of fatty liver diseases. The incidence of nonalcoholic fatty liver disorders (NAFLDs) and obesity are therefore intimately linked. It has been estimated that about 75% of obese subjects have NAFLD while 20% develop fatty liver disease with inflammation.

The amount of fat stored in liver is determined by the balance between fatty acid uptake, endogenous fatty acid synthesis, triglyceride synthesis, fatty acid oxidation, and triglyceride export. Changes in any of these parameters can affect the amount of fat stored in liver.

The excessive fat accumulation in adipose tissue, liver, and other organs strongly predisposes to the development of metabolic changes that increase overall morbidity risk. The metabolic abnormalities that often accompany obesity include hypertension, impaired glucose tolerance, insulin resistance leading to hyperinsulinemia, and dyslipidemia. Collectively, these abnormalities have been clustered into the metabolic syndrome.

Individuals that are diagnosed with metabolic syndrome have a significantly increased risk of developing cardiovascular disease (CVD) and type II diabetes. Observations have led to the view that obesity is a state of chronic low-grade inflammation that is initiated by morphological changes in the adipose tissue.

Obesity represents a major health threat. By targeting the inflammatory component, the progression of obesity towards insulin resistance and CVD might be slowed down.

So what can you do to fight inflammation and obesity? Big key items are a healthy lifestyle, regular fitness plan and good nutrition. You can also make sure that you take in good doses of anti-oxidants as part of your nutrition plan.

Antioxidants neutralize free radicals. In the last decade, scientists have proven that some antioxidants have anti-inflammatory properties. In addition to scavenging free radicals, there are antioxidants that actually block inflammation. The antioxidant effect (the blocking of certain oxidizing proteins) lowers the activation of inflammatory signals. Scientists have also found that combinations of certain antioxidants have greater effect than single antioxidants on certain types of inflammation.

Some key anti-oxidants and helpers are vitamin E, coenzyme Q10, lipoic acid, L-Carnitine, zinc, and magnesium amongst many others.

The best sources of antioxidants are vegetables, fruits, tea and wine. It is a good idea to get your antioxidants from a variety of sources. The more colorful your natural foods the better - yellow, orange, green, red, brown and blue-purple plant foods provide a variety of antioxidants, and the more brightly colored, the richer the food is in anti-oxidants. Foods are considered to be the preferred way of boosting antioxidant levels because they're thought to contain a wide array of antioxidant substances. Many of the them are also high in vitamins, minerals and fiber.

Some rich sources of antioxidants include (USDA Top 20): 
Small red bean (dried)
Wild blueberry
Red kidney bean (dried)
Pinto bean
Blueberry (cultivated)
Cranberry
Artichoke (cooked hearts)
Blackberry
Prune
Raspberry
Strawberry
Red delicious apple
Granny Smith apple
Pecan
Sweet cherry
Black plum
Russet potato
Black bean (dried)
Plum
Gala apple

So if your worried about where you stand with inflammation, consult your doctor for appropriate testing. Otherwise, work on your lifestyle, bad habits, fitness and nutrition and you'll be on your way to a much healthier day!

References:

http://dempseysresolution.getprograde.com/fighting-inflammation.html?advert_id=CN

http://www.arthritistoday.org/symptoms/inflammation/inflammation-heart-disease.php

http://www.wellnessletter.com/html/wl/2008/wlFeatured0108.html

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1783744/

http://www.osteoarthritisremedy.com/herbal-remedies/inflammationremedy/antioxidants-for-inflammation

Eric
Dempsey's Resolution Fitness